Peer reviewed papers published by Beta-O2

Links to manuscripts published by Beta-O2 scientists

Favorable outcome of experimental islet xenotransplantation without immunosuppression in a nonhuman primate model of diabetes

Barkai U, Rotem A, de Vos P. Survival of encapsulated islets: More than a membrane story. World J Transplant. 2016 Mar 24;6(1):69-90

Transplantation of macroencapsulated human islets within the bioartificial pancreas βAir to patients with type 1 diabetes mellitus
Per-Ola Carlsson1,2 | Daniel Espes1,2 | Amir Sedigh3 | Avi Rotem4 | Baruch Zimerman4 | Helena Grinberg4 | Tali Goldman4 | Uriel Barkai4 | Yuval Avni4 | Gunilla T. Westermark1 | Lina Carlbom3 | Håkan Ahlström3,5 | Olof Eriksson6 | Johan Olerud7 | Olle Korsgren7

Morozov VA , et al. Islet cell transplantation from Göttingen minipigs to cynomolgus monkeys: analysis of virus safety. Xenotransplantation. 2016 Jul;23(4):320-7.

Morozov VA, et al. Extended Microbiological Characterization of Göttingen Minipigs in the Context of Xenotransplantation: Detection and Vertical Transmission of Hepatitis E Virus. PLoS One. 2015;10(10):e0139893

Morozov VA , et al. Extended microbiological characterization of Göttingen minipigs: porcine cytomegalovirus and other viruses. Xenotransplantation, 2016, DOI: 10.1111/xen.12265

Ludwig B, et al. Transplantation of human islets without immunosuppression. PNAS – Proc Natl. Acad. Sci. USA. 110(47), 19054-8, Nov 19, 2013.

Neufeld T, et al. The efficacy of an immunoisolating membrane system for islet xenotransplantation in minipigs. PLoS One. 2013;8:e70150.

Barkai U, et al. Enhanced oxygen supply improves islet viability in a new bioartificial pancreas. Cell Transplant.2013;22:1463-76.

Semaan M, et al. Screening pigs for xenotransplantation: prevalence and expression of porcine endogenous retroviruses in Göttingen minipigs. Xenotransplantation. 2013;20:148-56.

Ludwig B, et al. Improvement of islet function in a bioartificial pancreas by enhanced oxygen supply and growth hormone releasing hormone agonist. Proc Natl Acad Sci U S A. 2012;109:5022-7.

Ludwig B, et al. A novel device for islet transplantation providing immune protection and oxygen supply. Horm Metab Res. 2010;42:918-22.

Links to related manuscripts

Long-term viability and function of transplanted islets macroencapsulated at high density are achieved by enhanced oxygen supply. Scientific REPOrTS | (2018) 8:6508 | DOI:10.1038/s41598-018-23862-w 1

Ludwig B, Ludwig S. Transplantable bioartificial pancreas devices: current status and future prospects. DOI: 10.1111/ajt.14642

Ludwig B, Ludwig S. Transplantable bioartificial pancreas devices: current status and future prospects. Langenbecks Arch Surg. 2015 Jul;400(5):531-40.

Colton CK. Oxygen supply to encapsulated therapeutic cells. Advanced Drug Delivery Reviews, Cell encapsulation and drug delivery. 2014, 67–68; 93–110.

Barkai U, et al. Bio artificial pancreas – the immune barrier and oxygen deficiency. Xenotransplantation. 2014;21:190.

Balyura, et al. Transplantation of bovine adrenocortical cells encapsulated in alginate. PNAS 2015; 112(8);2527-2532

Y. Evron, et. al. Oxygen Supply by Photosynthesis to an Implantable Islet Cell Device. Hormone and Metabolic Research, 2015; 47(01): 24-30.

Ludwig B, et al. Transplanting allo-islets without immunosuppression. Xenotransplantation. 2014;21:189.

Dolgin E. Encapsulate this. Nat Med. 2014;20(1):9-11.